Amoxicillin is effective in treating periodontitis. Patients with periodontitis will have a large mixture of bacteria in the periodontium, which is a chronic infection process, so taking anti-inflammatory drugs is effective in treating periodontitis. However, while taking amoxicillin, it is usually also recommended to combine it with metronidazole tablets or tinidazole tablets to treat periodontitis more effectively. For patients with periodontitis, long-term oral anti-inflammatory drugs are not recommended for treatment. The clinical treatment of periodontitis is based on local medication and local treatment. Local medication is mainly saline and hydrogen peroxide, which is used to thoroughly flush the gum surrounding and periodontal pockets, and iodine glycerin or minocycline hydrochloride ointment is applied in the periodontal pockets for local anti-inflammation. Local treatments for periodontitis include ultrasonic scaling, also known as scaling, which removes tartar and plaque from the gum surface and periodontal pockets, creating a good oral hygiene environment to treat periodontitis. For patients with very serious periodontal inflammation, these patients usually have deep periodontal pockets, and conventional ultrasonic scaling cannot yet completely remove tartar and plaque from periodontal pockets, and require deep cleaning, which mainly includes periodontal scaling, root planing, and even gum flap surgery for thorough treatment.