It is better to switch to Pentavalent when polio has already been given as Pentavalent adds polio vaccine to the quadruple vaccine, but at intervals greater than 28 days from the first polio vaccine. In terms of the types of diseases to be prevented, DPT5 is better than DPT4. The quadruple vaccine is for whooping cough, diphtheria, tetanus, and Haemophilus influenzae type B. The quadruple vaccine is for whooping cough and diphtheria. The Pentavalent vaccine is a polio vaccine added to the Quad vaccine, so it is better to change to Pentavalent. The polio vaccine is a common vaccine that is effective in preventing polio. After one injection of polio vaccine. If another dose of Pentavalent Vaccine is to be given, it is better to have an interval of more than 28 days from the first dose of Polio Vaccine because Pentavalent Vaccine contains Polio Vaccine. Clinically, when vaccination is given, it should be done in a specialized hospital to avoid incorrect vaccination, which may cause adverse consequences.