The causes of female masculinization are as follows: 1. External factors influence the intake of excessive androgens in the female body, such as the use of androgen therapy for patients with breast cancer or aplastic anemia. No matter the anticancer treatment of the former or the improvement of bone marrow hematopoietic treatment of the latter, long time treatment will make female patients gradually masculinize, which can be improved after stopping the drug; 2. Women suffering from polycystic ovary syndrome, the function of ovarian secretion of estrogen decreases, and androgens take the upper peak in the body, and the appearance of masculine performance appears. Suffering from androgen-secreting tumors, patients with increased androgen secretion in the body affect female characteristics and gradually appear male characteristics, such as increased sweat hair, growing beard, thickening voice, amenorrhea, etc.; 3, psychological factors, there are two aspects of genetics and external influence. Some girls in the process of growing up always in the psychological belief that they are boys, masculine behavior, some even married with women. There are also stimulated or family education problems, so that girls in the process of growing up psychologically serious skewed, gradually psychologically think they are boys, can be corrected through the treatment of psychologists.