Usually, pyriformis syndrome causes pain in the hip bone. The pain tends to radiate along the sciatic nerve and can also appear in the back of the thigh and calf. Piriformis syndrome is a syndrome caused when the sciatic nerve is compressed at the piriformis muscle. The hip bone is made up of three main parts: the hip bone, the sciatic bone and the pubic bone. Because the typical symptom of the disease is pain in the affected hip, and the pain radiates mainly along the sciatic nerve, pyriformis syndrome usually causes pain in the hip bone. In addition to pain in the buttocks, patients may also experience pain in the back of the thighs, calves, feet, etc. In severe cases, walking difficulties may occur, and the pain may be aggravated by factors such as cross-legged, bending over, lifting heavy objects, coughing, sneezing, and so on. Secondly, patients are often accompanied by atrophy of buttock or calf muscles, abnormal skin sensation, striated hard lumps and other symptoms. When the above symptoms occur, it is necessary to be vigilant that it is Pyriform Muscle Syndrome. Patients need to go to the hospital as soon as possible, and in most cases, the prognosis is good if they actively cooperate with the doctor’s treatment.