Quadruple therapy should pay attention to the principle of diet to light and easy to digest, do not drink alcohol, avoid eating stimulating food. Quadruple therapy is a combination of drugs used clinically to eradicate Helicobacter pylori. That is, a proton pump inhibitor such as omeprazole + a bismuth agent such as bismuth pectin + two antibiotics such as amoxicillin, clarithromycin for eradication treatment. Since antibacterial drugs need to be taken during the treatment, alcohol should not be consumed to avoid disulfiram-like reactions. Also to reduce the irritation of the gastrointestinal tract during the medication, the diet should be based on fresh fruits and vegetables. It is not recommended to consume greasy food such as cream and fatty meat; do not drink cold beverages and consume cold food such as ice cream; spicy and stimulating food such as chili, pepper and ginger should also be minimized. Quadruple therapy should be carried out under the guidance of a doctor.