Bone tumors are tumors that occur in the bone or its accessory tissues (blood vessels, nerves, bone marrow) and have a population incidence of about 0.01%. The pathogenesis of bone tumors is complex and there is no exact etiology. Malignant bone tumors develop rapidly and are difficult to diagnose and treat, which has been a difficult problem in orthopedic science and oncology. Therefore, the problem of bone tumor has plagued many families. Can bone tumor be cured? Can bone tumor be cured? How to make this “killer” not too cold? Next, we will talk about the things about bone tumor. Xiaohua, a senior high school boy who is doing his best to sprint for the college entrance examination, often felt pain in his legs recently. One day, he couldn’t stand it anymore, so he took time off to rest at home. His parents thought he was suffering from back and leg pain caused by studying too hard, or “growing pains” of developing and growing children. Because of the study tension and fear of delaying the revision, his parents did not pay much attention to it and did not take him to the hospital for examination. Recently, the pain intensified Xiaohua accompanied by teachers to the hospital orthopedics, the results of the examination was “osteosarcoma of the distal femur”, which is like a bolt from the blue for the family preparing for the college entrance examination. Why would a healthy and lively young man suddenly get bone tumor? Bone tumor is unfamiliar to many parents, but it is the most common malignant bone tumor that occurs in adolescents and has the characteristics of high malignancy and rapid development. If left untreated, the tumor can develop lung metastasis in a short period of time, leading to death of the patient. Therefore, once children are found to have regular bone pain in their legs and feet, especially in the adjacent joints, they must go to a specialized hospital for examination. Forty percent of patients delay treatment There are many clinical cases of bone tumors that are not detected at an early stage, so that the best time for treatment is missed. Whether early detection and diagnosis can be achieved depends largely on the vigilance of patients, family members and receiving doctors for bone tumors. For benign bone tumor, in the early stage, besides soreness and swelling, it usually appears as a slow-growing lump, which is usually counted by years and is not painful or itchy. For malignant bone tumor, the early symptoms will be pain or swelling around bone and joint, often more obvious at night, and not necessarily related to sports or trauma, etc. The lump will grow fast, usually measured in months. Sometimes there is also skin fever and even pathological fractures. Osteosarcoma usually develops insidiously, and because of the rapid growth of bones in adolescents, the pain caused by bone tumors is easily misdiagnosed as growing pains or thought to be general arthritis or sprains, which misses the best time for treatment. Some statistics show that 60% of the patients are already in the middle and late stage when they visit the doctor, and 40% of them are delayed because they cannot get timely diagnosis and standardized treatment. Bone tumor pain is a physiological phenomenon that occurs during the growth and development of adolescents, therefore, in daily life, many parents ignore the symptoms of “knee pain” of their children, thinking that it is caused by their children’s growing bodies or excessive activities such as naughty falls, which eventually delay the treatment of their children. Parents should always observe and inquire about their child’s development. If there is unexplained swelling and pain around the joints of the adolescent, which is not obviously related to sports or trauma, they should pay attention to the pain symptoms and patterns of the child. Many parents may mistakenly think that their children have growing pains or pain caused by sports injuries and do not take them seriously. Local general clinics are often unable to diagnose the disease correctly. Therefore, any patient who has bone and joint pain and the pain cannot be relieved after ten days should go to a specialist hospital for examination as soon as possible, or visit different tertiary hospitals to avoid any missed and misdiagnosed cases. In order to detect bone tumor at an early stage, parents and children should pay attention to the following conditions and should do further examination in time: 1.When the pain and swelling of limbs are not caused by trauma, inflammation or wind and cold, it should not be taken lightly; 2.The pain and swelling of the limbs are consistent and have the characteristics of fixity and persistence, especially at night and worsening day by day, adolescents must be highly alert; 3.Pain is an important symptom of malignant tumor. 3. Pain is an important symptom of malignant tumor, which is intermittent at the beginning, but later develops into persistent, more obvious at night, and worsens in late stage, affecting work, study and rest; 4. Is limb preservation or amputation better? If bone tumor is diagnosed, what should be done? At present, benign bone tumor or tumor-like lesion is mainly scraped or surgically removed, which generally has a low recurrence rate and most of them can be cured and have a good prognosis. For malignant bone tumors, the treatment effect is not so good, and long-term follow-up is required. As long as the standardized treatment includes preoperative neoadjuvant chemotherapy, regular and timely surgery, and postoperative chemotherapy, the current five-year survival rate of osteosarcoma can reach 70% to 80%, and the ten-year survival rate can reach 40%. Malignant bone tumors generally require extensive resection and even amputation. Is it better to preserve the limb or to amputate it? There are also many debates at present. Because malignant tumors can cause danger not only locally, but metastasize to other vital organs such as lungs through blood circulation. The premise of limb preservation surgery mainly depends on whether the doctor can completely remove the tumor and also protect the surrounding important blood vessels and nerves, which largely depends on the doctor’s medical technology and whether the tumor is discovered in time.” It should be noted that the current situation in China is that the rate of amputation is still relatively high compared with the developed countries in the West, mainly because most of the patients have been delayed for a long time when they come, and the mass is relatively large and affects the surrounding muscles and nerves and blood vessels, so it is difficult to perform limb-preserving surgery. Moreover, most of the primary hospitals do not have doctors specialized in bone tumors. We especially call on everyone to pay attention to bone tumor and be alert to bone tumor. In addition never trust folk remedies as the only means of treatment. At present, the most effective treatment is combined treatment, not just surgery, or just chemotherapy and radiotherapy, only integrated treatment can improve the long-term survival of patients.