Etiology】 Most of them are the result of hematogenous spread of tuberculosis secondary to pulmonary or mesenteric lymph node tuberculosis, or are caused by retrograde spread of adjacent tuberculosis lesions (ribs, sternum, pleura or axillary lymph nodes, etc.) via lymphatic vessels or direct spread. Clinical manifestations】 Commonly seen in women aged 20-30 years old, with a slow disease course. In the initial stage, there is one or several nodes in the breast without pain or tenderness, indistinctly demarcated from the surrounding tissues, often with skin adhesions, and the ipsilateral axillary lymph nodes may be enlarged. There is no clinical fever. The lump softens and forms a cold pustule; it may penetrate into the skin to form a fistula or sinus tract and exclude thin pus with cheese-like necrosis. In a few patients, the lump becomes hard through fibrosis, which changes the shape of the breast and invaginates the nipple. Diagnosis] The diagnosis of early stage breast tuberculosis is called difficult and often needs to be clarified by biopsy. After the formation of ulcers and sinus tracts, the diagnosis is not difficult. The fistula or ulcer is light blue-red in color, and the skin is edged with pale granulation tissue. Treatment】 Pay attention to rest, increase nutrition, and apply anti-tuberculosis drugs systemically. If the lesion is limited, the affected lesion can be removed. Generally, mastectomy should be avoided, and total mastectomy should be done only if the lesion is large.