Yusuf is the trade name, the generic name is ursodeoxycholic acid capsule, mainly for steroidal gallbladder stones, bile reflux gastritis and other diseases, the emergence of liver stones is generally not too related to this drug. Ursodeoxycholic acid capsule by inhibiting the reabsorption of cholesterol in the intestinal tract and reducing the secretion of cholesterol into the bile, thus reducing the saturation of cholesterol in the bile, so that cholesterol stones gradually dissolved, so generally does not cause liver stones. The occurrence of liver stones may be related to congenital genetic factors, or long-term consumption of high-fat, high-protein and high-calorie foods will further induce patients to develop intrahepatic bile duct stones. Adverse reactions such as loose stools or diarrhea may occur after use of the drug, and elderly patients should use the drug with caution. Ursodeoxycholic acid capsules should not be taken during the first trimester of pregnancy. The use of this medication is prohibited in cases of hypersensitivity to this drug or the ingredients of the formula, acute cholecystitis and cholangitis, biliary obstruction. In the event of intrahepatic stones, it is recommended to seek medical attention, follow the doctor’s instructions for further examination and targeted treatment or therapy with the help of the doctor.