There are three important indicators for the diagnosis of hepatocellular carcinoma: 1) The patient has a clear history of long-term chronic liver disease, such as hepatitis, cirrhosis, etc. 2) Imaging examination, such as ultrasound, CT or MRI, reveals a space-occupying lesion in the liver, and at the same time, such a space-occupying lesion has the characteristic of fast in and fast out imaging. That is to say, it is characterized by low-density changes in plain scanning, rapid enhancement in the arterial phase, and rapid de-enhancement in the portal phase. This is closely related to the liver, hepatocellular carcinoma and blood supply. Hepatocellular carcinoma mainly relies on hepatic artery for blood supply, so it rapidly strengthens in the arterial phase; 3. AFP, if AFP is clearly elevated, >400ng/mL or 200ng/mL, lasting for more than two months, and combining with the aforementioned imaging features, primary hepatocellular carcinoma can be diagnosed. Primary liver cancer can be diagnosed by clinical diagnosis without pathology.