The PARTAGE observational study, published in the February 2015 Journal of the American College of Physicians, noted that excessive application of antihypertensive drugs may carry an increased risk of death in more frail elderly people over 80 years of age. The study looked at 1127 elderly people over the age of 80 and compared the 2-year mortality rate between two groups with systolic blood pressure (normally referred to as high pressure) below 130 mmHg and those without. The results showed that the 2-year mortality rate was 32% in the group with a systolic blood pressure below 130 mmHg, which was 78% higher than the risk of death in the group with a blood pressure not below 130 mmHg. Although the study was observational and the population size was small, future larger controlled studies are needed to provide better evidence. Still, it suggests that we should not over-intensify blood pressure lowering in elderly people, especially those who are more debilitated. Therefore, we still need to follow the guideline recommendation that in the elderly, a target systolic blood pressure control of 150 or less is sufficient without excessive blood pressure lowering. Overall, it is better to treat chronic disease treatment in the elderly with slight adjustments and assistance, and overly aggressive treatment is not always beneficial.