Outpatient clinics often have more than 80 years old to see hypertension, they tend to fluctuate blood pressure, often go to the emergency room in the middle of the night because of elevated blood pressure to lower blood pressure, hoping to bring it down as soon as possible, and asked to lower the blood pressure to the same level as young people, in fact, the elderly have special physiological characteristics, lowering blood pressure also depends on the individual. According to 2013 statistics, China’s senior population over 80 years of age more than 23 million, and at an annual rate of 5% increase in this population, 70% to 90% suffer from hypertension, “how to lower blood pressure over 80 years of age hypertension to be safe?” To lower blood pressure safely and effectively, we must first understand the characteristics of hypertension in the elderly and the goal of lowering blood pressure. First, the characteristics of hypertension in the elderly 1, systolic blood pressure is mainly elevated, pulse pressure increases. That is, the people often say that the upper pressure is high, the lower pressure is not high, the gap between the upper and lower pressure is large, which is caused by vascular sclerosis. 2, abnormal circadian rhythm. Normal people have low blood pressure at night and high blood pressure during the day, but the circadian blood pressure rhythm disappears or reverses in the elderly. 3, blood pressure fluctuates greatly. The elderly tend to have the following conditions: a postural blood pressure fluctuations. b early morning hypertension. c postprandial hypotension. 4.White coat hypertension , pseudohypertension, and secondary hypertension are common in the elderly. Second, the blood pressure level of starting drug therapy and the target value of blood pressure lowering 1, the blood pressure level of starting drug therapy: ≥ 160 / 90 mmHg. 2, the goal of antihypertensive treatment: ① elderly patients without combined cardiac, cerebral and renal diseases, the target value of blood pressure < 145 ~ 150 / 90 mmHg. ② patients with combined cardiac, cerebral and renal diseases, a phased blood pressure control strategy, first lower the blood pressure to < 150 /90 mmHg, and if well tolerated, further reduce to <140 /90 mmHg. ③Blood pressure should not be lower than 130 /60 mmHg. ④Smoothly lowering blood pressure, it is safer to reach the blood pressure target within 3 months. The choice of antihypertensive drugs and the main precautions 1, an antihypertensive drug, small dose to start. 2, choose safe and effective, good compliance, long-acting antihypertensive drugs. 3, small doses of combined drugs have better antihypertensive effect.