These are two different diseases, but this is a more specialized issue, so I’ll try to be more general here. When we talk about Parkinson’s disease, strictly speaking, it should be called primary Parkinson’s disease. And Parkinson’s syndrome refers to secondary Parkinson’s syndrome, and Parkinson’s superimposed syndrome. Primary Parkinson’s disease, as the name implies, has no clear cause; secondary Parkinson’s disease is usually caused by traumatic brain injury, poisoning, drugs, cerebrovascular disease, tumors, inflammation, etc. The superimposed syndrome refers to Parkinson’s disease in addition to other neurological damage, such as severe brain atrophy, and so on. This is still rather abstract, and it is more intuitive to differentiate from the clinical manifestations. The age of onset of primary Parkinson’s disease is around 55 years old, while patients with the syndrome can be very young, and the disease progresses rapidly, the symptoms are more severe, there may be balance disorders at an early stage, easy to fall, slurred speech, and the effect of medication is not good, unlike primary patients who have a more obvious honeymoon period of medication. Then there is the fact that primary patients should have normal brain MRI, while most MRI images of patients with the syndrome are faulty. This explanation is easy to understand, but not very rigorous. In fact, even for experienced specialists, it is not easy to judge this problem. Therefore, it is necessary to consult a specialist in person.