Bilirubin-lowering drugs include ursodeoxycholic acid capsule, glycyrrhizic acid preparation, adenosylmethionine butanedisulfonate, etc. They should be regulated under the guidance of doctors. 1. Ursodeoxycholic acid capsule can inhibit the reabsorption of cholesterol and reduce the secretion of cholesterol into bile, thus leading to the gradual dissolution of cholesterol stones and lowering of sludged bilirubin, and it is mainly used for steroidal gallbladder stones and cholestatic liver disease. 2. Glycyrrhizic acid preparations, such as diammonium glycyrrhizinate injection and magnesium isoglycyrrhizinate injection, do not have the effect of directly lowering bilirubin, but also lowering bilirubin by protecting the liver cell membranes, reducing the degeneration of hepatocytes, and improving liver function. 3. Butanedisulfonic acid adenosylmethionine enteric-coated tablets can exogenously replenish adenosylmethionine and restore the physiological mechanism of bile secretion, mainly used for elevated bilirubin caused by intrahepatic cholestasis due to cirrhosis. Elevated bilirubin can cause jaundice, itchy skin and liver damage if not actively treated, so it is necessary to consult a doctor in time and standardize the use of medication under the guidance of a doctor.