Abdominal pain caused by smoking is suspected to be pain caused by the stimulation of the gastrointestinal mucosa by harmful substances in smoke. It is recommended to stop smoking, quit smoking as soon as possible, drink more water, eat a light diet, and then use acid-suppressing and gastric mucosa-protecting drugs, such as omeprazole, bismuth potassium citrate, and aluminum-magnesium plus. Life that smoking will mainly affect the respiratory organs such as the trachea, lungs, etc., but in fact smoke can also have a great impact on the gastrointestinal tract mucosa, because the nicotine, tar and other harmful substances in the smoke will enter the body through the mucosa of the digestive tract, thus stimulating the abnormal secretion of gastric juice, mainly stimulating the endocrine cells within the gastric mucosa to be hyperactive, so that they work at a high level leading to the secretion of gastric juice more than the normal amount of gastric juice secretion, which can lead to damage to the gastric mucosa. Thus destroying the gastric mucosa, which can lead to gastrointestinal dysfunction and also promote the occurrence of peptic ulcers. According to survey statistics, the incidence of duodenal ulcers in smokers is much higher than in non-smokers, smoking also increases the incidence of hypertension, diabetes, smoking can cause greater harm to themselves and others, it is recommended to quit smoking early.