Treatment of perforated intestinal tuberculosis should be in three areas: anti-tuberculosis drugs, symptomatic supportive therapy and surgery. Drugs should be applied under doctor’s guidance. 1. Anti-tuberculosis drugs: the main drugs are isoniazid, rifampicin, pyrazinamide, streptomycin, etc. The principles of anti-tuberculosis drug treatment are early, regular, whole course, appropriate amount, and combination. 2. Symptomatic supportive treatment: patients with intestinal perforation should be prohibited from fasting, anticholinergics can be used for abdominal pain, and patients with severe diarrhea should pay attention to the correction of disorders of water, electrolytes and acid-base balance. 3. Surgical treatment: perforation of intestinal tuberculosis may lead to massive intestinal bleeding, those patients who can not effectively stop bleeding after active resuscitation need surgical treatment, feasible repair, because the repair is carried out on the acute inflammation, active tuberculosis foci, the failure rate is very high, and should strive to carry out intestinal segmental resection anastomosis.