The blisters at the center of the face may be caused by stomach heat, dampness and heat in the spleen and stomach, or fire and heat in the liver and gallbladder, etc. It is recommended to make a clear diagnosis by combining with the symptoms of the whole body. 1. Stomach heat: If you eat a lot of spicy and deep-fried food for a long time, it can lead to stomach heat, blisters on the face, accompanied by dry mouth and thirst, like cold drinks, constipation, and easy to eat and hunger, etc., you can choose to clear the stomach and other drugs to treat it. 2. Damp-heat in the spleen and stomach: If the spleen and stomach are weak, the spleen loses transportation and digestion, and water and dampness stops inside, which results in heat, damp-heat in the spleen and stomach may appear, and facial blistering may also appear, accompanied by abdominal distension and chest tightness, sleepy limbs, lack of desire to eat and drink, and sticky and greasy stools, etc., and can be chosen to treat with drugs such as Zhongmanshenxie Pills. 3. Liver and gallbladder fire and heat: If the emotions and feelings are not smooth, depression and fire, can lead to liver and gallbladder fire and heat, liver fire inflammation, can lead to facial blistering, accompanied by burning pain in the coarseness of ribs and ribs, redness of the eyes and swelling pain, head distension and pain, irritability, etc., can choose Longguan Diarrhea Liver Pills, Diarrhea Qing Pills, etc. for treatment. The above mentioned medicines are recommended to be used under the guidance of a doctor. If air bubbles appear in the middle of the body, it is recommended to ask the doctor for a clear diagnosis and standardized treatment.