If a patient has frequent heartburn, the first thing to consider is cardiac neurosis due to plant nerve dysfunction, there will be frequent, disturbed heart, chest tightness and shortness of breath. This condition does not show significant changes in electrocardiogram and positive changes in coronary angiogram of the heart, but the clinical symptoms of the patient are relatively heavy. In addition, the above-mentioned conditions may occur in endocrine metabolic disorders, such as imbalance of estrogen and progesterone secretion in women during menopause and adolescence. In addition to hyperthyroidism and hyperadrenocorticism, which lead to disturbances in the internal environment, organic heart disease, such as coronary heart disease and myocarditis, may also cause symptoms of heartburn in some patients.