Teratozoospermia and miscarriage in relation to the birth of malformed children

  The clinic sees a large number of semen reports every day, and most of these patients have reports that suggest a simple teratozoospermia. Many patients ask the same question, doctor, will the fetus I give birth to be deformed, and if a couple comes in and not coincidentally if the couple has had a previous miscarriage, then the woman many blame the husband for the miscarriage because the other person had too many deformed sperm. Here I will make a brief elaboration on the relationship between simple deformed spermatozoa and miscarriage and the birth of deformed children, which I hope will be helpful.  First of all, we need to clarify how normal sperm and deformed sperm are determined and what the criteria for determining them are. The egg thinks it is handsome, it looks good, it is the normal form of sperm, the rest of course is deformed. The rest are of course deformed. So how can the egg judge how handsome and good looking the sperm is? If the sperm can pass through the zona pellucida, then it is handsome and good looking, and most of the rest are deformed. The problem is, a group of sperm rushing towards the oocyte, the sperm rushing in front may enter the zona pellucida, and the ones behind want to enter but there is no place, they can only stare outside! You can say that the first to go must be more handsome than the last to go in, good-looking. It is like a group of people to apply for several positions, most of them may be unsuccessful (because the post on a few), is it true that the unsuccessful people must not have talent, did not choose on must be inferior to the selected. We have to admit that the selected ones are certainly good enough, but we can’t deny the unselected ones. So the criteria for judging sperm morphology itself is somewhat problematic. This egg may find these sperm handsome, while another egg may find some other sperm handsome. European, Asian, and African eggs may think that the sperm that are handsome may be the same again. The sperm is not the same as the other sperm, so the report is open to question. If the results of multiple tests show that different people are suffering from aberrant spermatozoa, then the diagnosis of aberrant spermatozoa can be better.  The relationship with miscarriage: the current research reports have come to different conclusions, some observed a relationship between teratozoospermia and miscarriage, and some reports have concluded that there is no relationship between the two. However, there is no direct evidence to confirm a direct relationship between teratozoospermia and spontaneous abortion. Legally, according to the principle of the benefit of the doubt, at least for the time being, there is no direct relationship between miscarriage and teratozoospermia, and further studies and trials are needed to confirm this.  Relationship to the birth of deformed children: Most of the sperm deformities are in the head. Generally, sperm with head deformities have difficulty penetrating the zona pellucida of the oocyte to cause conception because penetration of the zona pellucida requires the release of acrosomal enzymes from the acrosome of the sperm head in order to dissolve the zona pellucida and allow the sperm to enter. This process is often hindered by head malformations, and secondly, sperm with tail malformations often have difficulty reaching the oocyte due to lack of viability, let alone penetrating the zona pellucida. In 2004, Mckenzie KJ reported that some absolutely malformed spermatozoa were fertilized by in vitro fertilization with oocytes, and in 21 clinical pregnancies, none of the babies were malformed. Therefore, at least for the time being, it is still not true that there is a direct relationship between teratospermia and the birth of malformed children.  Treatment: Although there is no relationship between teratozoospermia and miscarriage and the birth of malformed children, it does not mean that teratozoospermia is not harmful, or at least it may reduce your ability to conceive. The main treatment is to maintain healthy and good habits (quit smoking and drinking, don’t stay up late, exercise properly, avoid sauna and hot springs, try not to drink strong tea and coffee, eat more vegetables and fruits) and supplement some antioxidants (such as vitamin E, L-carnitine, coenzyme Q10, etc.).