Many people in life, no matter how big or small the disease can be treated with medication will not lightly choose other treatments, medication is a conservative treatment plan, especially for those major diseases, such as Parkinson’s disease, many people will choose medication, most patients are worried about the risks of surgery and other surgical treatments. So, can medication cure Parkinson’s disease? “The treatment of Parkinson’s disease is preferred to medication, but medication is not able to completely cure Parkinson’s disease, medication combined with surgery to better treat Parkinson’s disease.” Name: Mxw Gender: Male Age: 64 years old Condition at admission: The patient was admitted to the hospital with the main reason of “progressive limb stiffness and slow movement for 9 years”. The patient went to the hospital 9 years ago with stiffness and slow movement of the left hand, and was considered to have “lacunar cerebral infarction”, and was given infusion therapy without significant improvement in symptoms; 8 years ago, the stiffness of the left upper limb was worse than before, and tremor of the left upper limb appeared, and the left lower limb dragged when walking, so he went to the hospital again, and was diagnosed with “Parkinson’s disease”. Parkinson’s disease”, given methotrexate 1/2 tablet, amantadine and other drugs orally after the symptoms lessened than before, 3 years ago the patient left limb symptoms than before aggravated, and the right limb stiffness, starting difficulties, unable to get up, turn over, went to the hospital, adjusted methotrexate 1 tablet, oral symptoms after the previous relief; after the patient’s symptoms further aggravated, unable to walk independently, facial The patient’s symptoms were further aggravated, he could not walk independently, his facial expression was reduced, he had difficulty standing and walking, his stride was small, he had difficulty in turning to stop, and his muscle tone was significantly increased, so he came to our outpatient clinic, where he was diagnosed with “Parkinson’s disease” and his medication was adjusted. Parkinson’s disease” was admitted to the hospital. Preliminary diagnosis: 1. Parkinson’s disease Treatment: After admission to the hospital to improve the relevant examination and preoperative examination, there is no absolute contraindication to surgery, under local anesthesia + general anesthesia to perform directional bilateral deep brain electrical stimulation implantation treatment, the procedure went smoothly, the patient did not have special discomfort during and after the operation. The patient was given routine postoperative treatment of hemostasis, infection prevention, nutritional support, neurotrophy and symptomatic support. The patient recovered well and the wound healed well. At the time of discharge, the patient was in good general condition, with clear speech, good mental status and good wound healing. Prof. Wang Xuelian instructed that the patient could be discharged after checking the room. Discharge diagnosis: Parkinson’s disease. Discharge medical advice: 1. Discharge with medication: none 2. Advice to the patient: pay attention to rest and strengthen nutrition; 3. Health education: continue to take oral medication according to the preoperative medication regimen,; 4. Follow-up time: 1 month. From the case, we can know that this patient took a lot of medication for the treatment of Parkinson’s disease in the early stage, and when the condition worsened, he also controlled the condition by increasing the amount of medication, and later chose to have surgery when the situation was even worse, and still had to take medication in the later stage. This shows that the treatment of Parkinson’s disease is obviously not enough just by taking medication, and deep brain electrical stimulation therapy can better control the disease. “The treatment of Parkinson’s disease can be controlled by taking medication in the early stage, and when the effect of taking medication is not obvious, surgical treatment – deep brain electrical stimulation therapy can better help Parkinson’s disease patients to regain hope for life.”