Headache, fever and generalized soreness are seen in a variety of causes, most commonly seen in infectious factors, such as respiratory infections caused by viral infections or influenza, etc.; also seen in non-infectious factors, such as rheumatoid immune disease, malignant tumors and so on. 1. Infectious factors: When viral infection occurs, the body may develop fever, body temperature rises, the body’s energy consumption increases, oxygen consumption increases, leading to the accumulation of lactic acid in the muscles, causing generalized muscle soreness. 2. Non-infectious factors: such as rheumatoid immune disease, malignant tumors, often headache, fever, body aches, weakness and other symptoms, there will be wasting, loss of appetite, if necessary, timely access to hospitals. Fever, headache, body aches, must be timely medical treatment, do not treat yourself, so as not to delay the condition.