Various pathological types of thyroid cancer may require total thyroidectomy depending on the condition. 1. papillary thyroid cancer: when this type shows lateral thyroid involvement and even nearby lymphatic metastasis, it usually needs total thyroidectomy for treatment, which is conducive to reducing the recurrence rate of the disease. 2. Follicular thyroid cancer: this type of thyroid cancer can be treated by lobectomy, but if the lesions are found on both sides of the thyroid gland, or if the lesions are large and there are lymphatic metastases in the vicinity, it is recommended to choose total thyroidectomy. 3. Undifferentiated thyroid cancer and medullary thyroid cancer: these two types of thyroid cancer are highly malignant and prone to metastasis, and usually require total thyroidectomy for treatment. After total thyroidectomy for all types of thyroid cancer, levothyroxine tablets should be taken to replace thyroxine treatment, and regular review is needed.