Clinical diagnosis of prostate cancer needs to be considered from the following aspects: 1, patient symptoms, early prostate cancer does not have specific symptoms, usually accompanied by symptoms of prostate hyperplasia, mainly urinary frequency, urinary urgency, urinary difficulties, etc.; 2, physical examination, mainly refers to the trans-anal fingerprinting of the prostate, through the examination to find out whether there is a hardening of the texture, there is no obvious nodular hyperplasia and other manifestations; 3, the prostate tumor index examination, the most commonly used clinical test is the prostate-specific antigen, that is, PSA. 3, prostate tumor index examination, the most commonly used is the prostate specific antigen, that is, PSA, its normal range is 0-4ng/mL, if more than normal need to be alert to the possibility of tumor; 4, imaging tests, including ultrasound, magnetic resonance examination, to find out whether there are prostate nodules or lumps, especially peripheral band mass, the likelihood of tumors will be higher. If the above four aspects are combined, the possibility of prostate tumor requires prostate puncture biopsy. At present, in order to confirm the diagnosis of prostate cancer, in addition to surgery, prostate puncture biopsy is the only gold standard, and the diagnosis can only be confirmed by obtaining prostate tissues through puncture and discovering the cancerous cells through histopathological diagnosis.