Patients with myasthenia gravis generally have a severe preoperative condition, which is aggravated by surgical trauma after undergoing thymectomy with a different procedure. Therefore, the postoperative management of patients occupies an important position in their perioperative treatment. 1. At the end of surgery and after the patient first wakes up from anesthesia, the endotracheal tube should not be removed hastily, to ensure the usual airway, maintain effective breathing, and carefully observe the stable state of their neuromuscular strength. If necessary, ventilator for assisted breathing. 2.The endotracheal tube should be removed after the respiratory capacity is considered satisfactory, and the patient is required to breathe with a maximum negative pressure greater than 2cmH2O. 3.Normal mechanical ventilation and anticholinesterase drug therapy are important means to ensure the patient’s smooth recovery after surgery and prevent the occurrence of myasthenia gravis crisis. 4.Measure the patient’s spirometry to inhalation ratio and compare blood gas analysis before extubation. 5.For those who need long-term mechanical ventilation, choose tracheotomy.