Taking Rigliptin has a hypoglycemic effect, long-term consumption may have nasopharyngitis, cough, loss of appetite, nausea, vomiting, itchy skin and other adverse reactions, or there may not be any adverse reactions, depending on the person. Riglitazide is a dipeptidyl peptidase 4 (DPP-4) inhibitor, which can inhibit the degradation of GLP-1 (intestinal insulinotropic hormone-like polypeptide-1), promote insulin synthesis and secretion, and play a role in hypoglycemia, and can be used in the treatment of type 2 diabetes mellitus. Long-term use of Riglitazone may cause nasopharyngitis, cough, loss of appetite, nausea, vomiting, itching of the skin and other adverse reactions, but also back pain, myalgia, arthralgia, hypoglycemia and so on. Rigliptin should not be used in patients with a history of allergy to this drug. Riglitazone should be used under the supervision of a doctor and in case of discomfort, seek medical attention.