Frequent vague pain in the liver area is usually caused by chronic inflammatory irritation of the liver, or by the enlargement of the liver pulling on the liver envelope. The most common cause is fatty liver, in which excessive fat deposits in the liver cause the liver to enlarge and the pericardium to be mechanically stretched, resulting in a constant vague pain in the liver area. In addition, chronic hepatitis and cirrhosis, the inflammation of the liver stimulates the peritoneum, which can also cause vague pain in the liver area. In addition, some other causes of liver damage can have vague pain in the liver area, which is usually not effective through medication and may last for a longer period of time. Fatty liver by losing weight and controlling weight, if it gets better, the symptoms of vague pain in the liver area may get better. In addition, under normal imaging and biochemistry, some people feel discomfort in the liver area when they are angry, insomnia, or tired.