If the high risk HPV infection is still positive after Lipstick surgery, colposcopy is also needed. It is recommended not to have coitus for 3-7 days after the menstrual period is cleared, and the tests of leukorrhea routine, blood routine and coagulation time can be done if they are all normal to find out whether the cervical epithelium is already pathologically altered under the high-risk HPV infection and pathological diagnosis needs to be done, which will be based on the clinical diagnosis. The clinical diagnosis is based on the pathologic diagnosis. If the pathological diagnosis is negative, it is recommended to give regular review, and find abnormalities in time to deal with. If the pathology report is positive, different treatments will be given according to the results, such as localized physiotherapy, including laser therapy and cryotherapy, for low-grade lesions. If it is a high-grade lesion, clinically, it can be followed by Liparoscopic surgery.