Urine microalbumin over 1000mg/L is not normal, the normal value is 0~30mg/L, which indicates the existence of serious kidney injury, the possibility of nephrotic syndrome, chronic glomerulonephritis, diabetic nephropathy and other diseases. 1. Nephrotic syndrome, clinical with large amount of proteinuria, hyperlipidemia, hypoproteinemia, high degree of edema as the main symptoms, large amount of proteinuria is one of the necessary indicators to confirm the diagnosis, urinary microalbumin exceeds the normal range of the larger, there is a possibility of suffering from the disease. 2. Chronic glomerulonephritis, the basement membrane is damaged, glomerular filtration rate is reduced, a large amount of protein loss, urine protein is positive, urine microalbumin test can be significantly higher. 3. Diabetic nephropathy, due to poor blood sugar control, may lead to diabetic nephropathy, positive urine protein, swelling, weakness and other symptoms. Urine microalbumin abnormal patients, it is recommended to regular hospitals, under the guidance of physicians to improve the relevant examination, to clarify the cause of the disease, targeted treatment.