Hashimoto’s hypothyroidism interventional therapy is currently in the stage of continuous exploration, the therapeutic effect is not yet certain. Hashimoto’s hypothyroidism is an autoimmune disease with a certain genetic predisposition, which may be caused by a variety of factors that dysfunction the body’s immune system, the body produces autoantibodies against the thyroid gland, resulting in a large number of destruction of the thyroid cells, which ultimately leads to hypothyroidism. Clinical treatment for Hashimoto’s hypothyroidism is mainly aimed at supplementing thyroxine and correcting hypothyroidism. The etiology of Hashimoto’s thyroiditis is complex, and the pathogenesis is not very clear, so new treatments are constantly being explored, such as immuno-intervention therapy. Immuno-intervention therapy for Hashimoto’s hypothyroidism is a new treatment concept, the therapeutic effect is not yet very certain, and the clinical evidence is not sufficient. It is recommended that patients with Hashimoto’s hypothyroidism go to the endocrinology department of a local formal medical institution and take scientific and effective treatment under the guidance of the doctor according to their current condition.