China is now 45 years old before the women can play the HPV vaccine, there are some high-risk groups more need to play the HPV vaccine, common high-risk groups are as follows: 1, smoking women; 2, sexual life very early in life; 3, the number of sexual partners is very much women; 4, abortion times, the number of times of delivery, or have the basic immune system diseases of the women, are all high-risk factors of HPV virus infection. . That is why this group of women need the HPV vaccine even more. The current vaccine three kinds, such as bivalent, quadrivalent, nine-valent, at present can only be nine-valent vaccine in women before the age of 25 years, before the age of 45 years old women can play quadrivalent and bivalent.