Mosquito bites with serious redness and swelling and hard lumps can be improved by general treatment and medication. 1. General treatment: patients with insect bite dermatitis should do a good job of repelling insects in the environment, get out of the environment to avoid being bitten again. Avoid local scratching, can use soapy water or water to rinse the local, neutralize the acidic saliva secreted by mosquitoes. 2. medication: the presence of redness, swelling and severe hard lumps of insect bite dermatitis patients, you can follow the doctor’s instructions for external use of halometasone cream, hydrocortisone butyrate cream and other glucocorticosteroid drugs, anti-inflammatory, anti-itching effect. You can also take oral cetirizine, olopatadine hydrochloride and other antihistamines, with swelling, anti-allergic effect. For patients with severe redness and swelling with hard lumps of insect bite dermatitis, it is recommended to go to a regular hospital in time, and cooperate with the doctor for standardized treatment.