Is all psoriasis hereditary? Is it possible to have children with psoriasis? This is a very complicated issue, involving medical and social, psychological and other aspects. 1. According to medical statistics, if one parent has psoriasis, the possibility of children having the disease is 10-20%, but if both parents have psoriasis, the chances of children having the disease will rise to 50-60%. Therefore, in short, psoriasis has a certain degree of heritability, but as long as both parents are not sick, “nine out of ten” is not hereditary. 2, the heredity of psoriasis involves multiple genes, medicine has not yet found which specific genes will lead to the onset of the disease, so it is not possible to take out cells at the gamete stage, fertilized egg stage for genetic diagnosis, that is, the third generation of IVF can not avoid the disease; fetal stage or even after birth, it is not possible to find out whether the child will develop the disease in the future. The disease is not an infectious disease, and whether the mother or father develops psoriasis at the stage of conception and during pregnancy and breastfeeding does not affect the health of the child; the disease itself does not cause fetal malformation, nor does it increase the risk of infertility, and under the condition of safe medication, it does not affect fertility. 4, most female patients with psoriasis during pregnancy will be reduced without treatment, so there is no need to deliberately wait for the disease to heal before preparing for pregnancy, and can give birth earlier. 5, the existing topical drugs and ultraviolet light therapy and biological agents commonly used to treat psoriasis are safe for pregnant women, and we always have a way to control the disease without affecting fetal development. 6.In the next generation, people suffering from psoriasis will suffer less difficulties than people now. On the one hand, it comes from the progress of medicine. I can see the great progress in psoriasis treatment in nearly 20 years of medical practice, new drugs and new methods can effectively control the disease and greatly improve the quality of life of patients. Looking backward 20 years, I can foresee that medical progress and breakthroughs in the field of psoriasis are bound to accelerate. On the other hand, with the improvement of social civilization and the progress of public awareness, and the development of welfare protection system, patients will have less difficulties in life. Therefore we can hardly worry about our children’s future illnesses. They have the means. 7, even without psoriasis, children may still suffer from other major diseases, look at the current haze, perhaps the chances of a psoriasis patient’s children suffering from lung cancer and liver cancer are higher than suffering from psoriasis, as well as diabetes, high blood pressure, etc. etc. In fact, the impact of psoriasis may have been able to ignore some. What drugs can a psoriasis mother use? There are not many psoriasis patients preparing for pregnancy with a disease severe enough to require oral medication. If there are oral medications that need to be taken very carefully, those that are commonly used to effectively treat psoriasis, such as methotrexate, have a certain degree of reproductive toxicity and require that the medication be stopped for six months before pregnancy. Avelox is also a commonly used oral drug, which is clearly teratogenic, and the instructions require women to stop taking it for two years to completely exclude the accumulation. However, the teratogenicity of the drug is closely related to the concentration and does not mean that the presence is teratogenic, but requires a certain amount and chance. Generally speaking, the risk of getting pregnant again after stopping the drug for more than three months is still relatively low. Avastin mainly affects embryonic development and has no effect on sperm, so the male partner can prepare for pregnancy without waiting when he stops taking the drug. Other oral medications, such as cyclosporine A, are still relatively safe and can be used for pregnancy after stopping the medication.