The need for medication for mitral regurgitation is determined by the severity of the condition. For mild, chronic mitral regurgitation with no obvious symptoms, no medication is usually needed. For patients with moderate to severe mitral regurgitation, commonly used drugs include angiotensin-converting enzyme inhibitors, diuretics, anticoagulants, and so on. 1. Angiotensin-converting enzyme inhibitors: such as captopril, etc., often applied to chronic mitral regurgitation, can improve ventricular remodeling and prevent patients from deterioration of cardiac function. Anuric renal failure, hyperkalemia, double renal artery stenosis, etc. are prohibited. 2. Diuretics: such as furosemide, etc., can help relieve patients’ symptoms such as dyspnea due to mitral regurgitation. Use with caution if you have renal insufficiency or high blood potassium. 3. Anticoagulants: such as warfarin, etc., for patients with severe heart failure, history of embolism and within three months after mitral valve repair need to use anticoagulant therapy. The above drugs should be used under the guidance of a regular physician, do not self-medication.