Patient: The ulcer was found two years ago, and I took Nexium, last year the stomach bleeding, and now I still have frequent pain. H. pylori is still positive. How to cure it? Chen Xueqing, Department of Gastroenterology, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, China: Resistant letter treatment alone cannot cure Helicobacter pylori (HP). Generally speaking, the eradication program includes an acid-suppressing drug (such as proton pump-resistant letter), one or two antibiotics (such as clarithromycin, ampicillin, dysentery, levofloxacin, etc.), with (or without) a bismuth agent. Due to the abuse of antibiotics, many are resistant. So how to use, or please go to the local specialist hospital to prescribe better. Patient: It was prescribed at a specialist hospital with Nesin, clarithromycin (or amoxicillin), and Daxil. But the C14 test is still positive. Now there may be drug resistance, so I have to take Nexium for pain. Dr. Chen: Can you give me a treatment plan? Chen Xueqing, Department of Gastroenterology, The First Affiliated Hospital of Guangzhou Medical College: You can ask your local doctor to take a look at the consensus report on the treatment of H. pylori infection in the Chinese Medical Journal 2008,88(10):652-656, which has many remedial options. Those are all prescription drugs, and it would be unhelpful for me to prescribe them to you on the Internet, which would only lead to more abuse of antibiotic drugs.