Patients with hypertension need to stop drinking and smoking. If you are in a long-term drinking state, blood pressure cannot be better controlled, and you may take 2-3 kinds of drugs orally, but your blood pressure cannot be controlled below 140/90mmHg. For hypertensive patients need to stop drinking, after quitting alcohol and then regular oral medication control can drop another 10-20mmHg. so quit drinking is very important for hypertension control, of course, also need to carry out lifestyle improvement. However, some hypertensive patients, after 2-3 kinds of antihypertensive drugs including smoking cessation and alcohol cessation, still cannot control their blood pressure to below 140/90mmHg, which is called persistent hypertension. This part of patients need to clarify the primary cause, such as secondary hypertension, metabolic system abnormalities, pheochromocytoma, Cushing’s syndrome, primary aldosteronism, diabetic nephropathy, renal artery stenosis and other diseases can cause hypertension. For such patients the primary disease should be controlled and all hypertensive patients must abstain from alcohol.