The removal of the uterus does not usually have an effect on estrogen, but if the ovaries are removed at the time of surgery, estrogen production can be affected. The uterus, which is the site of conception of the fetus and production of menstruation, will lose its reproductive function after removal, causing menstruation to disappear. However, the uterus does not have the function of secreting hormones, and the organ that secretes estrogen is the ovary. If there is no damage to the ovary during the removal of the uterus, estrogen secretion is usually not affected. Excessive estrogen may lead to the emergence of diseases such as uterine fibroids, uterine adenomyosis, and uterine leiomyosarcoma, which require hysterectomy for treatment when the condition is serious. If the ovaries are removed during surgery, estrogen production will be affected. In order to avoid premature menopausal syndrome due to low estrogen after surgery, it is necessary to take estrogen supplements as prescribed by the doctor. Consultation with your doctor is recommended for details.