Recurrent herpes is usually caused by the human herpes simplex virus, mostly invades the skin-mucosal junction and develops as a result of various triggers such as fever, cold, exertion, emotional distress, and other stimuli. Symptoms may include patches of small blisters or papules on the skin and mild neuralgia. The main treatment for recurrent herpes is medication. Recurrent herpes can be treated with topical medications only for superficial skin mucosal infections, while systemic antiviral medications should be given to patients with more severe lesions, disseminated infections or important organ involvement. Topical treatment can be applied topically with acyclovir ointment or penciclovir cream. In case of secondary bacterial infection, mupirocin ointment may be used for treatment. When there is vesicular exudation, topical wet compresses of furacilin solution can be used. Herpes in the oral cavity requires attention to keep the mouth clean and rinse with Neosporin solution. Systemic treatment of recurrent herpes simplex can be intermittent, preferably starting within 24 hours of the appearance of prodromal symptoms or lesions. Medications may be acyclovir, valacyclovir, or famciclovir. In case of herpes recurrence, do not scratch with your hands to avoid pus in the infected area. In daily life, you need to strengthen physical exercise, maintain an optimistic state of mind and improve immunity.