Very low platelets can be remedied by transfusion of single platelets of the same blood type, subcutaneous injection of recombinant human thrombopoietin, intravenous glucocorticoids or gammaglobulin, oral platelet-boosting drugs, and treatment of the primary disease. 1. Transfusion of single platelets of the same blood type is the fastest treatment to raise the platelet count, but the duration of maintenance is shorter, about 3~4 days at the longest. Platelet-boosting drugs such as subcutaneous injection of recombinant human thrombopoietin, oral ricoagulin tablets, and aminopterin tablets are suitable for all thrombocytopenic patients, but the efficacy varies. 2. Treating the cause of thrombocytopenia is the key to improving platelet count. For example, patients with primary immune thrombocytopenia can be treated with intravenous glucocorticosteroids such as dexamethasone or gammaglobulin. Thrombocytopenia caused by leukemia, multiple myeloma, lymphoma, myelodysplastic syndrome, aplastic anemia and other hematologic diseases, as well as thrombocytopenia caused by viral hepatitis, systemic lupus erythematosus, rheumatoid arthritis and other diseases need to be treated for the primary disease. For example, acute leukemia is treated with chemotherapy with drugs such as cytarabine. When platelets are very low, patients may have bleeding manifestations such as petechiae and ecchymosis of the skin and mucous membranes, bleeding or blood vesicles of the oral and nasal mucous membranes, and may also have serious complications such as spontaneous intracranial hemorrhage and gastrointestinal hemorrhage, so platelet counts need to be raised immediately. Patients are advised to consult the hematology department in a timely manner to actively clarify the cause of the disease, and then formulate a treatment plan after the specialist and assessment of the condition.