It is not clear what will happen to polycystic liver, most patients will be stable for years if their condition is well controlled, without much effect. If polycystic liver patients affect the liver and kidney function, liver and kidney failure may occur, seriously affecting the quality of daily life of patients. Polycystic liver will cause patients to experience symptoms such as abdominal distension, abdominal pain, dyspnea, etc. If the condition can be effectively controlled after timely and regular treatment, it will not have much effect on patients. If polycystic liver is combined with polycystic kidney, it affects the function of liver and kidney, and damage occurs, and in serious cases, liver and kidney failure may occur, affecting the quality of daily life of patients. If polycystic liver is also combined with infection, portal hypertension, rupture and bleeding of cysts, malignant changes, etc., the condition is not controlled and stabilized, and the patient’s life and health may be endangered in serious cases. Patients with polycystic liver need to pay attention to rest, avoid strenuous exercise, and try to avoid rupture and bleeding of cysts caused by external impact on the right upper abdomen. Patients need to go to the hospital regularly for follow-up, if the patient has other physical discomfort, should promptly inform the doctor to avoid adverse effects.