Hot sputum means that the sputum is thicker and is yellowish. This usually indicates that the sputum is caused by a bacterial infection, which may be an upper respiratory tract infection or a lower respiratory tract infection. In case of upper respiratory tract infection, it is usually accompanied by swelling and pain in the throat or symptoms of nasal congestion, runny nose or yellow nasal discharge, which requires antibiotics for treatment. For the symptoms of upper respiratory tract infection, you can take some oral cefradine or cefixime, cephalexin or penicillin amoxicillin, amoxicillin clavulanic acid potassium, also can. In addition, sputum fever may also be a lower respiratory tract infection, including bronchitis or pneumonia. If there is a lower respiratory tract infection, oral medication is often not effective enough, and intravenous antibiotics are needed to treat the lower respiratory tract infection, such as intravenous ceftriaxone, penicillin or cefoperazone.