There is no saying which one is better, etoricoxib or celecoxib, it needs to be given according to the patient’s condition and under the guidance of the doctor’s appropriate choice. Etoricoxib is mainly used for the treatment of osteoarthritis in acute and chronic stages, acute gouty arthritis, primary dysmenorrhea, etc. It has anti-inflammatory, analgesic and antipyretic effects. Celecoxib is mainly used for the relief of osteoarthritis, adult rheumatoid arthritis, acute pain in adults, relief of ankylosing spondylitis, etc. The two drugs specifically treat different conditions, there is no which drug is better. When taking etoricoxib, symptoms such as infection facial edema, hypertension, allergy, etc. may occur, and it is forbidden to use it if you are allergic to the drug, peptic ulcer and other patients. Care should be taken to avoid combining with other NSAIDs, use with caution in patients with obvious signs of dehydration, and is not recommended for patients with advanced kidney disease. Note the possibility of cardiovascular events in patients with no previous cardiovascular events. Some patients may experience abdominal pain, diarrhea, dyspepsia, dizziness, headache, and rhinitis while taking celecoxib. It is contraindicated for those who are allergic to celecoxib or any other ingredient in the drug, and for those who are allergic to sulfonamide. Carefully monitor cardiovascular thrombosis, try to use the lowest effective dose for the shortest possible time. It is recommended to use the drug under the guidance of a doctor and in strict compliance with medical advice, not to use the drug blindly or change the dosage of the drug without authorization, in order to avoid adverse effects on the body and the emergence of other diseases.