Tetrapod Decoction Pill can relieve some of the symptoms of thyroid nodules, but the specific use of the medicine needs professional medical guidance. It is mainly composed of soft-shelled turtle shell glue, Colla Corii asiatica, honeycomb, rat worm, soft-shelled turtle shell, dung beetle, saltpeter, firewood, scutellaria and other medicines, which have the efficacy of activating blood circulation and removing blood stasis (to promote the blood circulation and eliminate the stasis of blood in the body), and softening and dispersing knots (to soften and disperse the hard nodules), and it can be clinically used to treat coercive subjunctival nodules and other symptoms. According to Chinese medicine theory, the pathogenesis of thyroid nodules mainly includes phlegm and stagnant stagnation, qi depression and phlegm obstruction, and spleen deficiency and phlegm accumulation, etc. It can be treated by regulating qi and relieving depression, softening and dispersing hard lumps and activating blood circulation and removing stagnation. Therefore, turtle shell decoction pill is useful in treating thyroid nodules. It should be noted that the adverse effects of this drug are not clear, and pregnant women and allergic people are forbidden to take it. It is necessary to strictly follow the doctor’s instructions to regulate the use of drugs, prohibit selfish use of drugs.