The main function of the glomerulus is filtration function, and the glomerular filtration rate (GFR) parameter is an important parameter to assess the filtration function of the kidney, and the reference value is clinically set at (100±20) ml/min, that is, normal adults are generally in the normal state of 80-120 ml/min. The formula is (140-age) × body weight ÷ blood creatinine (mg/dL) ÷ 72, and women multiply 0.85 on top of this, which is the more used and more classic formula for assessing glomerular filtration rate. However, this value decreases to varying degrees with age, and typically the glomerular filtration rate decreases by 10 ml/(min*1.73m2) every 10 years after age 40, and by age 80, the glomerular filtration rate decreases to about half of the glomerular filtration rate value at age 40. It is also important to note that women experience a significant increase in glomerular filtration rate during pregnancy, which can gradually decrease to normal after delivery. If a patient’s examination reveals that the glomerular filtration rate decreases at a faster rate than normal, the presence of kidney-related diseases such as renal failure, renal insufficiency, adrenal cortical insufficiency, renal arteriosclerosis, or possibly advanced diabetes, hypertension, hypothyroidism, etc. is considered.