The main complications after ERCP surgery include bleeding, perforation, severe pancreatitis, and infection, which are the four main complications. The first three of these complications, if very serious, are fatal and are the most serious complications. ERCP is generally very safe, there is a mortality rate, but the percentage is not very high, it may be 0.0% per thousand, the highest may reach 2 per thousand. Many doctors tell their patients that ERCP is a minor and minimally invasive surgery, but in fact it is not a minor surgery, it has certain surgical risks, and it is a class IV surgery, which is the most technically difficult and risky surgery. The most serious postoperative complications, namely bleeding, perforation and severe pancreatitis, are three fatal complications. There are treatments for each complication, and if bleeding is present, endoscopic treatment is preferred. If endoscopic treatment is not effective, interventional treatment is possible. If effective treatment cannot be performed under intervention, finally, that is, surgical open treatment, but it has the problem of recurrence, and almost 99% of postoperative bleeding can be treated endoscopically to achieve hemostasis. In addition, perforation, now after the improvement of endoscopic level perforation can be endoscopically repaired. Severe pancreatitis, nowadays, drugs and various methods can treat severe pancreatitis, and its mortality rate is decreasing year by year, and the total mortality rate is still below 2 per 1,000.