Leukocytes may decrease during menstruation because hormonal changes in the body cause the uterine lining to fall off and vaginal bleeding occurs. Vaginal bleeding is easy to cause neutrophilic leukopenia, during menstruation due to the body’s weakness and reduced resistance, easy to be infected by viruses leading to the phenomenon of leukopenia. If the leukopenia is simple and there is no discomfort, it is considered physiologic and does not need to be treated. If accompanied by cold, cough, fever and other symptoms may be a viral infection, it is best to take antiviral drugs to treat. If there are blood diseases, allergic diseases, tuberculosis, the use of chemotherapeutic drugs can also cause leukopenia will cause corresponding symptoms. It is necessary to go to the hospital in time for the relevant examination, according to the specific circumstances to choose the appropriate treatment, and at the same time recommended to strengthen the diet and nutrition to enhance the body’s resistance.