No significant sequelae have been identified with the HPV vaccine, but there are some side effects. The cervical cancer vaccine has been out for a total of more than a decade, and there are more than 200 million vaccination shots worldwide. in 2017, the World Health organization (WHO) has a position paper that talks about vaccine side effects, the main local symptoms are pain, redness, swelling, and hard nodules at the injection site, this has a high probability of occurrence, but most of them can be relieved within 48 hours, and some patients will have a low fever, usually <38°C, which can be relieved within 48 hours. The best age for HPV vaccination is in the late teens, before sexual intercourse, and the WHO's goal is to have more than 90% of women vaccinated with HPV by age 15. Currently teenage girls in Europe and the United States are on the immunization schedule, and there are currently no significant teratogenic effects on fertility. Pregnancy is usually possible after 3 doses, and if pregnancy occurs during the injection, abortion is not recommended, regular checkups are sufficient, and it does not cause immune system disorders, etc., or increase the risk of such diseases.