Uremic encephalopathy, most scholars believe that the primary cause is toxin accumulation, caused by high levels of toxins. Secondly, there may also be uremia caused by secondary parathyroid hormone elevation, secondary hyperparathyroidism caused. Knowing the cause, treatment can be carried out through the cause of the disease. 1, to actively remove the patient’s toxin level, the main ways include peritoneal dialysis and hemodialysis, because ordinary hemodialysis can only remove small and medium-sized molecular toxins, for the large and medium-sized molecules of toxins removed poorly, so in the ordinary dialysis based on the addition of hemoperfusion or hemodiafiltration can be used as a way of eliminating the toxins. 2, treatment of secondary hyperparathyroidism For the treatment of secondary hyperparathyroidism, we can actively regulate the disturbance of the internal environment, correct the metabolic acidosis, regulate the metabolism of calcium and phosphorus, and reduce the parathyroid hormone by taking drugs such as alfacalcitol.