Stones at the end of the ureter can cause pain, hematuria, difficulty in urination, and abnormal symptoms in other organs. 1. Pain: renal colic or ureteral colic may occur. Renal colic is characterized by paroxysmal pain in the lower back or upper abdomen; ureteral colic is characterized by pain that radiates along the course of the ureter in the body to the surrounding testicles, labia, and other parts of the body. 2. hematuria: most patients are microscopic hematuria, only after microscopic examination of the blood cells found in the urine, a few patients present naked eye hematuria. The severity of hematuria is related to the stone’s damage to the ureteral mucosa. 3. Difficulty in urination: If the stone causes obstruction at the end of the ureter, it may lead to difficulty in urination. 4. Other symptoms: Stones may sometimes irritate other organs, leading to nausea, vomiting and other symptoms. If any of the above symptoms occur, it is recommended to consult a doctor in time and take active treatment under the doctor’s guidance.