Anesthetic by paralyzing the central nervous system so that patients temporarily do not perceive pain, which is conducive to the patient’s cooperation with the examination or treatment, in general, there will be anesthesiologists to monitor the indicators of patients throughout the operation, adjusting the dose of anesthetic at any time, the clinical situation will not occur more anesthetic, and anesthetic metabolism by the body can be excreted on its own, will not cause significant impact on the human body. Anesthetics can be divided into general anesthetics and local anesthetics, if improper application of excessive doses of anesthetics, will have adverse effects on the human body: a. General anesthetics 1, respiratory depression: the use of an overdose of general anesthetics will have a strong respiratory depression, as evidenced by the reduction in tidal volume and respiratory rate slowed, and even lead to apnea; 2, cardiac arrest: some general anesthetics have an inhibitory effect on the myocardium and vasodilator effect, overdose will Resulting in a significant drop in blood pressure, slowed heart rate, reduced cardiac output, when injected in large doses may also cause shock due to cardiac arrest; 3, liver and kidney dysfunction: the metabolic process of drugs and metabolites have a certain degree of impact on liver and kidney function, so the application of too much anesthetic drugs may cause nephrotoxicity. Second, local anesthetics 1, mild manifestations: if the toxic reaction is mild, manifested as mental state excitement, increased blood pressure, nervousness and shortness of breath, etc., can appear dizziness, tinnitus, hyperphonia, drowsiness, chills, panic and disorientation; 2, severe manifestations: if the drug dose is too large, loss of consciousness can occur, and show tremors of the facial muscles and limbs. Once convulsions or convulsions occur, respiratory and circulatory failure may result from respiratory distress. In addition, improper use of anesthetics may also cause allergic reactions, hives, throat edema, bronchospasm and other symptoms, which may also be life-threatening. At the same time, the same dose concentration of anesthetic overdose for different age groups also varies, for children the impact on their body organ function is more serious, because their body organs are fully developed, the ability to metabolize anesthetics is lower, and the side effects are correspondingly greater. In addition, people of advanced age or with liver and kidney insufficiency also lack the ability to metabolize anesthetic drugs compared to normal people.