The probability of intestinal metaplasia progressing to gastric cancer is about 5%, but if intestinal metaplasia develops atypical hyperplasia, the probability of developing into cancer can be increased to 40%. Intestinal metaplasia is a disease in which normal gastric mucosal epithelial cells are replaced by intestinal epithelial cells, which is commonly seen in patients with chronic gastritis. According to the different pathological types of metaplasia cells, it can be classified into small intestinal metaplasia and colon metaplasia, etc. Generally speaking, small intestinal metaplasia has a better degree of cell differentiation, while colon metaplasia has a poorer degree of cell differentiation, and the probability of intestinal metaplasia progressing to gastric cancer is about 5%. In addition, if atypical hyperplasia occurs in intestinal metaplasia, the probability of progression to gastric cancer will be greatly increased to 40%. If intestinal metaplasia is detected on examination, since the type of intestinal metaplasia varies from person to person, the treatment should not be generalized, so please follow the doctor’s instructions for review or treatment.