I. What are the precautions in growth hormone treatment? Under the guidance of the doctor, the correct dose of rhGH should be injected; it should be injected one hour before going to bed every night; it is better for parents to learn how to inject by themselves to avoid waste; the injection site should be changed; the exercise should be adhered to appropriately during the period of treatment, which is conducive to the full absorption of the drugs. It must be reviewed in 3 months under the same ruler and the same laboratory conditions to be judged scientifically, and it is not possible to compare the methods of different laboratories when reviewing in the field. It is better not to adjust the dosage and stop the drug by yourself. What are the side effects of growth hormone therapy? Local transient reactions at the injection site (pain, numbness, redness, swelling, etc.) and symptoms of fluid retention (peripheral edema, arthralgia or myalgia), the incidence of which has been less; antibody production, which may affect the efficacy of the treatment, but the incidence of aqueous agents is low; hypothyroxinemia; temporary hypoglycemia; femoral head necrosis, slipping; idiopathic intracranial pressure increase: headache, vomiting, etc.; the possibility of inducing tumors: no clear evidence so far. clear evidence. C. People with family history of tumor and long-term application of supraphysiological dose of growth hormone need to be cautious. The growth hormone currently used is genetically recombinant, and its molecular structure is exactly the same as that of human growth hormone, and since it is a replacement therapy, the occurrence of side effects is relatively rare. However, it is still necessary to follow your doctor’s advice and have regular follow-up visits to your hospital’s specialist clinic during the course of growth hormone treatment. Regular measurement of height, IGF-1, IGFBP-3, T4, TSH, blood glucose and insulin tests should be performed here, so that the dose of GH can be adjusted in time and thyroxine can be supplemented. Bone age should be checked once every six months. Sexual development should be observed during the course of treatment and treated as needed. Those suspected of having intracranial lesions should be noted to repeat cranial MRI etc. periodically.